Perforating and nonperforating indications in repeated surgeries for Crohn’s disease

Table 3 Univariate and multivariate analysis of risk factors associated with postoperative recurrence after second surgery

Covariates	Univariate			Multivariate
	HR	95%CI	P value	HR	95%CI	P value
Preoperative duration	0.998	0.990-1.007	0.666	1.001	0.991-1.011	0.872
Interval from first to second	1.001	0.992-1.010	0.831
Age at diagnosis	1.012	0.984-1.041	0.406
Sex	0.804	0.368-1.755	0.583
Appendectomy	0.822	0.419-1.610	0.567
Smoking history	0.918	0.323-2.606	0.872	1.228	0.371-4.065	0.737
Preoperative treatment	1.349	0.667-2.752	0.405
Perianal disease	1.554	0.673-3.592	0.302	1.448	0.593-3.532	0.416
Age	1.008	0.980-1.036	0.590	1.009	0.977-1.042	0.579
Location	1.130	0.798-1.600	0.491	1.182	0.802-1.742	0.397
Perforating indication	2.036	1.043-3.968	0.037	1.919	0.959-3.846	0.065
Resection range	0.955	0.682-1.337	0.788
IASCs	0.862	0.378-1.966	0.725

IASCs: Intra-abdominal septic complications.