Associations between coagulation factor XII, coagulation factor XI, and stability of venous thromboembolism: A case-control study

doi:10.12998/wjcc.v10.i9.2700

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Mar 26, 2022 (publication date) through Jan 25, 2025

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Control Study

World J Clin Cases. Mar 26, 2022; 10(9): 2700-2709
Published online Mar 26, 2022. doi: 10.12998/wjcc.v10.i9.2700

Table 4 Association between factor XII antigen and factor XI antigen and the stability of deep venous thrombosis: Comparisons between patients with deep venous thrombosis and deep venous thrombosis and pulmonary embolism

	Cut-off¹	DVT	DVT + PE	χ²	OR	95%CI	P value
FXII:Ag	≤ 68.485	39	37	0.197	0.832	0.369-1.876	0.407
FXII:Ag	> 68.485	19	15	0.197	0.832	0.369-1.876	0.407
FXI:Ag	≤ 130.117	51	37	5.535	3.151	1.178-8.427	0.019
FXI:Ag	> 130.117	7	16	5.535	3.151	1.178-8.427	0.019

¹Cut-off values for factor XII antigen (FXII:Ag) and factor XI antigen (FXI:Ag) were selected based on the 95^th percentiles of FXII:Ag and FXI:Ag in patients with deep venous thrombosis and pulmonary embolism.

FXII:Ag: Factor XII antigen; FXI:Ag: Factor XI antigen; CI: Confidence interval; DVT: Deep venous thrombosis; OR: Odds ratio; PE: Pulmonary embolism.

Citation: Meng Y, Li Y, Ye YJ, Ma Q, Zhang JB, Qin H, Deng YY, Tian HY. Associations between coagulation factor XII, coagulation factor XI, and stability of venous thromboembolism: A case-control study. World J Clin Cases 2022; 10(9): 2700-2709
URL: https://www.wjgnet.com/2307-8960/full/v10/i9/2700.htm
DOI: https://dx.doi.org/10.12998/wjcc.v10.i9.2700