Associations between coagulation factor XII, coagulation factor XI, and stability of venous thromboembolism: A case-control study

Table 1 Characteristic of patients, presented as mean ± SD

	DVT (n = 58)	DVT + PE (n = 53)	Control (n = 61)	P value1
Mean age (yr)	61.6 (14.9)	56.8 (18.3)	61.7 (8.34)	0.57
Male (%)	44.0	58.3	45.0	0.76
Hypertension (%)	20.0	8.33	30.0	0.78
Diabetes (%)	8.00	0	20.0	0.62
CAD (%)	6.00	8.33	15.0	0.85
Smoking (%)	28.0	16.7	30.0	0.81
WBC (109/L)	8.16 (4.30)	9.95 (3.63)	5.49 (1.80)	0.002
Neutrophil, %	72.0 (12.7)	77.3 (8.14)	59.9 (8.32)	0.002
Platelet (109/L)	213.6 (62.8)	203.2 (82.3)	193.8 (46.4)	0.57
hs-CRP (mg/L)	8.19 (3.30)	9.21 (2.62)	1.63 (1.50)	< 0.001
hs-TNT (ng/mL)	0.08 (0.19)	0.02 (0.02)	0.01 (0.001)	0.63
FDP (mg/L)	25.4 (39.8)	33.5 (32.5)	1.62 (2.57)	0.009
FIB (g/L)	3.60 (1.38)	4.08 (1.30)	2.64 (0.39)	0.002
NT-proBNP	203.8 (229.3)	1038 (1653)	205.6 (555.0)	0.015
D-Dimer (mg/L)	8.64 (14.0)	12.2 (11.5)	0.72 (1.08)	0.001

¹P value was calculated using ANOVA test for continuous variables and Kruskal-Wallis test for categorical variables.

CAD: Coronary artery disease; DVT: Deep venous thrombosis; FDP: Fibrinogen degradation products; FIB: Fibrinogen; hs-CRP: High-sensitivity C-reactive protein; NT-proBNP: N-terminal pro-B-type natriuretic peptide; PE: Pulmonary embolism; WBC: White blood cells; hs-TNT: High-sensitivity troponin T.