Prognostic and biological role of the N-Myc downstream-regulated gene family in hepatocellular carcinoma

Figure 1 Expression of N-Myc downstream-regulated gene family genes in the Oncomine and The Cancer Genome Atlas databases. A: messenger RNA (mRNA) expression of N-Myc downstream-regulated gene (NDRG)1, NDRG2, NDRG3, and NDRG4 among various types of cancer using the Oncomine databases. The number in the cells indicate the number of datasets with statistically significant up-expression (red) or down-expression (blue) (cancer vs corresponding normal tissue); B: mRNA expression of NDRG1, NDRG2, NDRG3, and NDRG4 in tumor and normal samples in The Cancer Genome Atlas-liver hepatocellular carcinoma (LIHC) cohort; C: The paired mRNA expression of NDRG1, NDRG2, NDRG3, and NDRG4 between tumor and normal samples in The Cancer Genome Atlas-liver hepatocellular carcinoma cohort; D: The representative protein expression of NDRG members in hepatocellular carcinoma and normal liver tissue from the Human Protein Atlas.