Primary duodenal dedifferentiated liposarcoma: A case report and literature review

Figure 2 Features of tumor cells. A: The tumor was located in the submucosal layer of the duodenum (Hematoxylin-and-eosin stain, ×20); B: At a higher magnification, undifferentiated tumor cells were shown to have marked nuclear atypia with brisk mitotic activity (Hematoxylin-and-eosin stain, ×200); C: Immunohistochemistry revealed positivity for MDM2 in the tumor cells (Immunohistochemistry, ×200); D: MDM2 amplification was detected by MDM2/CEN12 fluorescence in situ hybridization assay (MDM2-green signals, CEN12-red signals, ×1000).