Two methods of lung biopsy for histological confirmation of acute fibrinous and organizing pneumonia: A case report

Table 1 Laboratory examinations

Laboratory examinations	Result
Blood gas	pH: 7.477, PO2: 71 mmHg, PCO2: 34.1 mmHg
Routine blood	WBC: 10.70 × 109, N%: 80.6%, HGB: 106 g/L, PLT: 583 × 109
CEA, Cyfra21-1, NSE	Negative
Coagulation	PT: 12.4 s, APTT: 28.2 s, Fib: 8.77 g/L
Liver biochemistry	ALT: 18 U/L, AST: 12 U/L, Prealbumin: 78 mg/L, ALB: 29.4 g/L
BNP	Normal
Nucleic acid testing for COVID-19	Negative
ESR	96 mm/h (0-20 mm/h)
PCT	Normal
CRP	143 mg/L (< 8.0 mg/L)
Serum HIV antibody	Negative
Tuberculosis-SPOT	Negative
(1,3)-beta-D-glucan assay	Negative
Galactomannan	Negative
CrAg	Negative
Bronchoalveolar lavage fluid	No bacteria, No aspergillus, No Tuberculosis, No Cryptococcus
Blood culture	Sterile
Respiratory pathogen profile detection	Negative
Lymphocyte subsets	CD4: 337 cells/μL, CD3: 590 cells/μL
Immunological test
Antinuclear antibodies	Positive, titer 1:100
nRNP/Sm	Weakly positive
Sm	Weakly positive
Ds-DNA	Negative
ENA	Negative
ANCA	Negative
ACA	Negative
Anti-CCP	Negative
Rheumatoid factor	Normal
IgE	257 IU/mL (< 100)
Immunoglobulins and complement	Normal

PO₂: Partial pressure of oxygen in the blood; PCO₂: Partial pressure of carbon dioxide in the blood; ESR: Erythrocyte sedimentation rate; PCT: Procalcitonin; CRP: C-reactive protein; CrAg: Cryptococcal capsular antigen; ANA: Anti-nuclear antibodies; RF: Rheumatoid arthritis factor; ENA: Extractable nuclear antigen profile; CCP: Cyclide polypeptide; HIV: Human immunodeficiency virus; CEA: Carcinoembryonic antigen; NSE: Neuron specific enolase; BNP: Human brain natriuretic peptide; ANCA: Anti-neutrophil cytoplasmic antibody; IgE: Anti-immunoglobulin E; Sm: Anti-Smith antibody; nRNP: Nuclear ribonucleoprotein.