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©The Author(s) 2022.
World J Clin Cases. Dec 26, 2022; 10(36): 13321-13336
Published online Dec 26, 2022. doi: 10.12998/wjcc.v10.i36.13321
Published online Dec 26, 2022. doi: 10.12998/wjcc.v10.i36.13321
Patients, n | Leakage | P value | |
Absent, n = 522 | Present, n = 61 | ||
Mean age, yr | 59.7 ± 17.2 | 68.2 ± 10.7 | 0.0002 |
Age, yr | |||
< 65 | 223 (92.2) | 19 (7.8) | 0.09 |
≥ 65 | 299 (87.7) | 42 (12.3) | |
Sex | |||
M | 263 (87.4) | 38 (12.6) | 0.08 |
F | 259 (91.9) | 23 (8.1) | |
Albumin, g/dL | |||
< 3.5 | 117 (84.8) | 21 (15.2) | 0.006 |
≥ 3.5 | 466 (92.1) | 40 (7.9) | |
CEA, ng/mL | |||
< 5 | 247 (89.5) | 29 (10.5) | 0.4 |
≥ 5 | 336 (91.3) | 32 (8.7) | |
Hemoglobin, g/dL | |||
< 10 | 291 (88.2) | 39 (11.8) | 0.02 |
≥ 10 | 292 (93.0) | 22 (7.0) | |
Prognostic nutritional index points | |||
< 40 | 130 (81.8) | 29 (18.2) | 0.0001 |
≥ 40 | 453 (93.4) | 32 (6.6) | |
Concomitant diseases | |||
Yes | 259 (87.6) | 37 (12.4) | 0.1 |
No | 263 (91.7) | 24 (8.3) | |
Weight loss | |||
Yes | 81 (82.7) | 17 (17.3) | 0.01 |
No | 441 (90.9) | 44 (9.1) | |
Smoking habits | |||
Yes | 201 (88.6) | 26 (11.4) | 0.5 |
No | 321 (90.2) | 35 (9.8) | |
Alcohol habits | |||
Yes | 71 (94.7) | 4 (5.3) | 0.1 |
No | 451(88.8) | 57 (11.2) | |
Bowel preparation | |||
Complete/adequate | 336 (93.1) | 25 (6.9) | 0.0007 |
Poor | 186 (83.8) | 36 (16.2) | |
Blood transfusions | |||
No | 299 (93.2) | 22 (6.8) | 0.002 |
≥ 1 unit | 223 (85.2) | 39 (14.8) | |
Mean tumor distance from anal verge in mm | 89.0 ± 21.0 | 71.0 ± 32.0 | 0.0001 |
Neoadjuvant treatment | |||
Yes | 349 (88.8) | 44 (11.2) | 0.4 |
No | 173 (91.1) | 17 (8.9) | |
Mean hospital stays in d | 7.0 ± 2.1 | 29.2 ± 13.4 | 0.0001 |
- Citation: Brisinda G, Chiarello MM, Pepe G, Cariati M, Fico V, Mirco P, Bianchi V. Anastomotic leakage in rectal cancer surgery: Retrospective analysis of risk factors. World J Clin Cases 2022; 10(36): 13321-13336
- URL: https://www.wjgnet.com/2307-8960/full/v10/i36/13321.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v10.i36.13321