Genetic changes in refractory relapsed acute myeloid leukemia with NPM1 mutation: A case report

doi:10.12998/wjcc.v10.i35.13058

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Dec 16, 2022 (publication date) through Aug 18, 2024

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Dec 16, 2022; 10(35): 13058-13063
Published online Dec 16, 2022. doi: 10.12998/wjcc.v10.i35.13058

Table 1 Gene testing before chemotherapy

Gene	Variation content
NPM1	Exon 12
ASXL1	Exon 12 c.3759T>C; p.S1253S
DNMT3A	Exon 2 c.27C>T; p.P9P
TET2	Exon 9 c.4140T>C; p.H1380H
TET2	Exon 3 c.652G>A; p.V218M c.3117G>A; p.S1039S
FLT3-ITD	No gene mutation was detected

Citation: Wang SL. Genetic changes in refractory relapsed acute myeloid leukemia with NPM1 mutation: A case report. World J Clin Cases 2022; 10(35): 13058-13063
URL: https://www.wjgnet.com/2307-8960/full/v10/i35/13058.htm
DOI: https://dx.doi.org/10.12998/wjcc.v10.i35.13058