Value of inflammatory mediator profiles and procalcitonin in predicting postoperative infection in patients with hypertensive cerebral hemorrhage

Table 4 Comparison of inflammatory mediator profile indices and procalcitonin levels between the two groups of patients, pre- and postoperatively (mean ± SD)

Index	Infection group (n = 80)	Non-infection group (n = 191)	t/χ2 value	P value
IL-2 (ng/L)
Preoperative	1.28 ± 0.35	1.23 ± 0.24	1.356	0.176
POD	2.62 ± 0.87a	1.78 ± 0.53a	9.725	< 0.001
IL-4 (ng/L)
Preoperative	1.06 ± 0.31	0.98 ± 0.26	2.179	0.030
POD	3.68 ± 1.01a	2.35 ± 0.76a	11.873	< 0.001
IL-6 (ng/L)
Preoperative	3.21 ± 1.94	2.87 ± 0.88	3.447	0.001
POD	11.28 ± 3.27a	8.64 ± 2.13a	7.870	< 0.001
IL-10 (ng/L)
Preoperative	2.75 ± 0.89	2.53 ± 0.68	2.209	0.028
POD	8.72 ± 1.94a	6.53 ± 1.85a	8.762	< 0.001
TNF-α (ng/L)
Preoperative	1.73 ± 0.46	1.58 ± 0.51	2.272	0.024
POD	6.58 ± 2.04	3.91 ± 0.94	14.755	< 0.001
IFN-γ (ng/L)
Preoperative	0.86 ± 0.25	0.80 ± 0.19	2.151	0.032
POD	3.18 ± 0.97	2.76 ± 0.84	3.583	< 0.001
PCT (μg/L)
Preoperative	1.55 ± 0.42	0.51 ± 0.19	28.087	< 0.001
POD	1.83 ± 0.56a	0.63 ± 0.21a	25.667	< 0.001

^aP < 0.05 vs the same group preoperatively.

IL: Interleukin; POD: Postoperative day; TNF-α: Tumor necrosis factor-α; IFN-γ: Interferon-γ; PCT: Procalcitonin.