Coptis, Pinellia, and Scutellaria as a promising new drug combination for treatment of Helicobacter pylori infection

Figure 4 Network analysis of predicted Coptis, Pinellia, and Scutellaria targets and differentially expressed Helicobacter pylori genes. A: Venn diagram of Coptis, Pinellia, and Scutellaria (CPS) indicates targets and differentially expressed genes in Helicobacter pylori-associated gastritis (HAG); B: Protein-protein interaction diagram of CPS and HAG; C: Cellular component, biological process, and molecular function analysis of gene ontology pathway enrichment; D: Kyoto Encylopedia of Genes and Genomes pathway enrichment analysis. CPS: Coptis, Pinellia, and Scutellaria; HAG: Helicobacter pylori-associated gastritis; GO: Gene ontology; BP: Biological process; CC: Cellular component; MF: Molecular function; KEGG: Kyoto Encylopedia of Genes and Genomes.