Inflammatory myofibroblastic tumor of the central nervous system: A case report

Table 1 Summary of 49 cases of inflammatory myofibroblastic tumor of the central nervous system reported in the literature since 2000

Ref.	Age in yr/sex	Duration of symptom in mo	Main symptoms and signs	Location	Contrast enhancement	Tumor diameter in cm	ALK expression	Main treatment	Chemotherapy	Prognosis
Present case	67/F	3	Diplopia	Left middle cranial fossa	Intense	2.4	Negative	GTR	None	No recurrence
Wang et al[5], 2019	21/F	0.5	Blurred vision	Right frontal lobe	Intense	10.0	Negative	GTR	None	No recurrence
Wang et al[5], 2019	60/M	N/A	Gait disturbance	Cerebellar hemisphere	Intense	N/A	Negative	GTR	None	No recurrence
Wang et al[5], 2019	48/F	Several	Paranoid	Right temporal lobe	Intense	5.3	Negative	GTR	None	No recurrence
Wang et al[5], 2019	20/F	0.75	Headache	Right temporal lobe	Intense	5.0	Positive	GTR	None	7 mo after 1st surgery
Wang et al[5], 2019	82/F	6	Memory decrease	Right temporal lobe	Intense	N/A	N/A	GTR	None	No recurrence
Wang et al[5], 2019	51/F	1.5	Headache	Cerebellar hemisphere	Intense	N/A	N/A	Biopsy	Steroid	N/A
Kuang et al[5], 2016	53/M	12	Blurred vision	Pineal	Intense	N/A	N/A	GTR	None	No recurrence
PascualGallego et al[7], 2013	47/F	N/A	Headache	Left temporooccipital lobe	Intense	N/A	Negative	GTR	None	4 mo after 1st surgery
Denis et al[19], 2013	26/M	3	Headache, blurred vision	Left frontal lobe	Intense	2.0	Positive	GTR	None	2 mo after 1st surgery
Denis et al[19], 2013	17/F	N/A	Seizures	Left frontal lobe	N/A	N/A	Positive	GTR	None	2.5 yr after 1st surgery
Denis et al[19], 2013	65/F	N/A	Blurred vision	Occipital lobe	Intense	5.0	Negative	STR	None	No recurrence
Denis et al[19], 2013	43/M	6	Headache	Orbit	Intense	N/A	Negative	GTR	None	No recurrence
Denis et al[19], 2013	7/M	N/A	N/A	Right temporal fossa	N/A	2.0	Positive	GTR	None	1.5 yr after 1st surgery
Denis et al[19], 2013	24/M	N/A	N/A	Left temporal lobe	N/A	N/A	Positive	GTR	None	2 yr after 1st surgery
Kolenc et al[18], 2013	77/F	N/A	Right partial motoric seizures	Left temporal lobe	Intense	N/A	Negative	Biopsy	Corticosteroids	No recurrence
Moss et al[14], 2012	36/F	N/A	Diplopia	Left middle cranial fossa	Intense	N/A	Negative	STR	Corticosteroids	24 mo after 1st surgery
Moss et al[14], 2012	50/F	5	Headache	Cavernous sinus	Intense	N/A	Negative	Steroid	None	N/A
Kato et al[28], 2011	60/M	N/A	Gait disturbance	Cerebellar	Intense	1.8	Negative	GTR	None	No recurrence
de Oliveira et al[27], 2009	7/M	3	Headache	Right temporal fossa	Intense	4.0	Positive	GTR	None	24 mo after 1st surgery
Lui et al[2], 2009	60/F	N/A	Blurred vision	Cerebral falx	Intense	N/A	Negative	GTR	Radiation therapy	No recurrence
Lui et al[2], 2009	52/F	N/A	N/A	Right ventricle	Intense	N/A	Negative	GTR	None	No recurrence
Lui et al[2], 2009	45/M	N/A	Left-sided weakness	Right frontal lobe	N/A	N/A	Negative	GTR	None	No recurrence
Lui et al[2], 2009	26/F	6	Blurred vision	Left occipital lobe	Intense	N/A	Negative	Biopsy	Corticosteroids, thalidomide	No recurrence
Swain et al[6], 2008	8/M	N/A	Attention deficiency	Left temporal lobe	Intense	N/A	Negative	STR	None	No recurrence
Swain et al[6], 2008	28/F	N/A	Seizure	Left occipital lobe	Intense	0.8	Positive	GTR	None	No recurrence
Swain et al[6], 2008	30/M	N/A	Headache	Posterior fossa	N/A	N/A	Negative	GTR	Radiation therapy	No recurrence
Swain et al[6], 2008	31/F	1	Headache	Right frontal lobe	N/A	N/A	N/A	GTR	None	No recurrence
Swain et al[6], 2008	74/F	N/A	Headache, seizures	Right parietal lobe	N/A	3.8		GTR	None	No recurrence
Swain et al[6], 2008	0.8/F	N/A	Seizures	Right temporal lobe	N/A	8.4		GTR	None	No recurrence
Miyahara et al[20], 2008	73/M	1	Gait disturbance	Paracele	N/A	N/A	N/A	GTR	Steroid	Died of complications
Miyahara et al[20], 2008	48/M	N/A	Memory decrease	Paracele	N/A	N/A	N/A	GTR	Steroid	No recurrence
Miyahara et al[20], 2008	18/M	N/A	N/A	Paracele	N/A	N/A	N/A	GTR	Steroid	No recurrence
Miyahara et al[20], 2008	63/F	N/A	Headache	Paracele	N/A	N/A	N/A	GTR	Steroid	No recurrence
Miyahara et al[20], 2008	50/M	0.3	Blepharoptosis	Left orbit, cavernous sinus	Intense	1.5	Negative	Biopsy	Corticosteroids	Progressive reduction
Jeon et al[1], 2005	43/M	N/A	Dizziness	Orbit, falx, sup. sagittal sinus, tentorium	N/A	N/A	Negative	STR	Corticosteroids	12 yr after 1st surgery
Jeon et al[1], 2005	31/M	N/A	Headache, ptosis	Cavernous sinus	Intense	1.5	Negative	GTR	None	No recurrence
Jeon et al[1], 2005	41/M	N/A	N/A	Temporal lobe	Intense	N/A	Negative	STR	None	No recurrence
Jeon et al[1], 2005	29/M	N/A	Aphasia	Temporal and frontal lobes	Intense	N/A	Negative	Steroid	None	No recurrence
Jeon et al[1], 2005	42/M	N/A	N/A	Subdura	Intense	N/A	Negative	GTR	None	No recurrence
Jeon et al[1], 2005	50/M	N/A	Seizures	Frontal lobe	Intense	5.0	Negative	STR	None	No recurrence
Jeon et al[1], 2005	52/F	N/A	Seizures	Occipital lobe	Intense	N/A	Negative	GTR	None	No recurrence
Jeon et al[1], 2005	24/F	N/A	Diplopia	Orbit	Intense	N/A	Negative	GTR	None	No recurrence
Jeon et al[1], 2005	65/F	N/A	N/A	Occipital lobe	Intense	4.0	Negative	GTR	None	7 yr after 1st surgery
Roche et al[10], 2004	20/F	0.3	Headache	Left temporal lobe	Intense	N/A	N/A	STR	Corticosteroids	Dramatic decrease in the mass size
Hausler et al[11], 2003	N/A/M	N/A	Seizures	Left temporal lobe	N/A	N/A	Negative	STR	None	No recurrence
Hausler et al[11], 2003	15/M	N/A	Seizures	Occipital lobe	Intense	N/A	N/A	STR	Radiation therapy	No recurrence
Hausler et al[11], 2003	17/F	N/A	Headache	Left frontal lobe	Intense	6.0	Positive	GTR	None	20 mo after 1st surgery
Buccoliero et al[9], 2003	70/M	6	Partial loss of vision	The bottom of the frontal lobes	Intense	2.0	Negative	Biopsy	Corticosteroids, radiation therapy	No remission

ALK: Anaplastic lymphoma kinase; F: Female; GTR: Gross total resection; M: Male; N/A: Not available; STR: Subtotal resection.