Evaluation of gut dysbiosis using serum and fecal bile acid profiles

Table 1 Correlation between the relative abundance of different fecal microbial taxa and serum or fecal deoxycholic acid (DCA)/(DCA + cholic acid) ratio (n = 46)

Fecal microbial taxa	DCA/(DCA+CA)
	Serum	Feces
Bifidobacterium	0.2136	0.0683
Lactobacillales	-0.5326a	-0.6830a
Bacteroides	0.1836	0.3031c
Prevotella	-0.0342	0.2693
Clostridium cluster IV	0.2282	0.4307b
Clostridium subcluster XIVa	0.5217a	0.7659a
Clostridium cluster IX	0.0710	0.0208
Clostridium cluster XI	-0.0631	-0.0053
Clostridium cluster XVIII	0.0348	-0.0425
Others	-0.0102	-0.0637

^aP < 0.001.

^bP < 0.01.

^cP < 0.05.

DCA: Deoxycholic acid; CA: Cholic acid. Pearson’s correlation coefficients were calculated using serum and feces from 26 healthy controls and 20 patients, including 6 with Crohn’s disease, 6 with ulcerative colitis, 4 with liver cirrhosis, and 4 with other gastrointes- tinal diseases (pancreatic cancer, colon cancer, ischemic small bowel disease, and alcoholic liver disease). This table was summarized from the Inflammatory Bowel Diseases 2018[24].