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©The Author(s) 2022.
World J Clin Cases. Nov 26, 2022; 10(33): 12365-12374
Published online Nov 26, 2022. doi: 10.12998/wjcc.v10.i33.12365
Published online Nov 26, 2022. doi: 10.12998/wjcc.v10.i33.12365
Table 2 Ocular clinical characteristics
Case | Gender/age (yr) | Chief complains | Ocular symptoms | Sites of orbital Lesions and Size | Operation treatment | Pathological diagnosis | Extraocular involvement |
1 | Male/44 | Enlarged left cheekbone mass for 8 mo | Left eyelid drooping, blurred vision three months later | Left eyelid drooping, blurred vision | Endoscopic tumor resection via nasal sella approach in March 2019 | Pasmacytoma of sellar region and clivus, infiltrating bone and submucosal | Left cheekbone mass 3 cm × 3 cm and mid-sternal mass 6 cm × 4 cm |
2 | Female/41 | Left eye socket swollen, lightly proptosis for more than one year | Left eye socket swollen, slightly proptosis and/or eye movement disorders | Left tear gland, mass size was unknown | The thyroid mass and left orbital lacrimal gland mass in May 2018 and April 2019 | left lacrimal gland plasmacytoma | Skull bone destruction and thyroid mass |
3 | Male/54 | Diagnosed with MM because of lung infection and elevated globulin in September 2011 | Blurred vision and proptosis and/or eye movement disorders in the right eye 2 yr later | The right orbital muscle and the left medial and lateral rectus muscles in orbital CT, mass size was unknown | No | No | Skull, ribs, lumbar skin, and mediastinum. The right ninth rib and L5 paravertebral multiple soft tissues, the largest mass reached 4.9 cm × 4.4 cm. |
4 | Male/42 | Diagnosed with MM because of bone pain in December 2007 | Blurred vision in left eye more than 3 yr later | Retina in left eye by head and eye MRI, mass in left retro-ocular choroid, size was 0.3 cm × 0.2 cm | Topical laser treatment | No | Cervical, thoracic and sacral vertebral bone lesion |
5 | Female/39 | Pain in the arch of the eyebrow and blurred vision in February 2010 | Pain in the arch of the eyebrow and blurred vision | left orbit mass size was 2.8 cm × 2.6 cm in PET-CT | Left orbital mass, bilateral uterine appendage and left breast mass excision in February and September 2010, respectively | Left orbital plasmacytoma | Bone lesion of thoracic vertebra ,Left breast, and ovarian mass, diagnosed with MM 8 mo later, left breast mass size was 12 cm × 10 cm in chest CT |
6 | Female/37 | Diagnosed with MM because of bone pain and increased creatinine in 2011 | Blurred vision in both eyes more than 4 yr later | Optic canal lesions in both eyes by head and eye MRI, the soft tissue mass were 1.5 cm × 0.8 cm and 0.9 cm × 0.3 cm in the right and left part | No | No | Sacral wing, sphenoid, clivus bone and pituitary |
7 | Female/33 | Diagnosed with MM because of Bone Pain and Lumbar Mass Biopsy in July 2014 | Discomfort and proptosis and/or eye movement disorders in the right eye more than 4 yr later | Right orbital inner and outer wall and musculoskeletal space mass, the right orbital mass was about 1.5 cm in diameter | Lumbar fracture internal fixation and tumor resection, right orbital tumor resection in July 2014 and March 2019, respectively | Right orbital plasmacytoma | Multiple bone destruction throughout the body |
- Citation: Hu WL, Song JY, Li X, Pei XJ, Zhang JJ, Shen M, Tang R, Pan ZY, Huang ZX. Clinical features and prognosis of multiple myeloma and orbital extramedullary disease: Seven cases report and review of literature. World J Clin Cases 2022; 10(33): 12365-12374
- URL: https://www.wjgnet.com/2307-8960/full/v10/i33/12365.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v10.i33.12365