Clinical features and prognosis of multiple myeloma and orbital extramedullary disease: Seven cases report and review of literature

Table 1 Baseline clinical characteristics

Items	Data
Age (yr)	41.4
Gender: M/F (cases)	3/4
Type of MM: IgGk/k (cases, %)	5 (71.4)/2 (28.6)
Stage of ISS: I/II/III (cases)	3 (42.9)/2 (28.6)/2 (28.6)
High-risk cytogenetics in FISH: 1q21+ (cases, %)	2 (28.6)
Features of EMD (cases)	2 (28.6)
Spinal cord/thyroid/breast/armpit soft tissue/ovary/pleural effusion/brain	2/2/2/2/2/1/1/0
≥ 2 sites (cases, %)	6 (85.7)
≥ 5 cm diameter (cases, %)	2 (28.6)
PC (%)	2.5
Calcium > 2.75 (mmol/L, C)	0
Creatinine > 176.8 μmol/L (mmol/L, R) (cases, %)	1 (14.3)
Hemoglobin < 100 (g/L, A) (cases, %)	1 (14.3)
Bone lesion (B) (cases, %)	7 (100)
Albumin < 35 g/L (cases, %)	0
β2-MG ≥ 5.5 mg/L (cases, %)	1 (14.3)
LDH > 240 U/L (cases, %)	1 (14.3)

M: Male; F: Female; MM: Multiple myeloma; ISS: International Staging System; IgG: Immunoglobulin G; k: k light chain; FISH: Fluorescence in situ hybridization; EMD: Extramedullary disease; PC: Plasma cell % in bone marrow; β 2-MG: β 2-microglobulin; LDH: Lactatedehydrogenase.