Protective effect of recombinant human brain natriuretic peptide against contrast-induced nephropathy in elderly acute myocardial infarction patients: A randomized controlled trial

Table 2 Renal indexes after primary percutaneous coronary intervention in the two groups

	Placebo	rhBNP	P value
Serum creatinine (mol/L)
Preoperative	72.35 ± 15.38	74.13 ± 16.28	0.521
24 h	85.74 ± 19.21	83.26 ± 18.12	0.449
48 h	101.55 ± 21.22	80.59 ± 19.46	0.001
72 h	88.15 ± 18.72	76.29 ± 16.55	0.007
Cystatin C (mg/L)
Preoperative	0.91 ± 0.22	0.93 ± 0.21	0.596
24 h	0.95 ± 0.25	0.96 ± 0.31	0.839
48 h	1.07 ± 0.37	0.93 ± 0.32	0.020
72 h	1.02 ± 0.30	0.88 ± 0.25	0.004
Creatinine clearance rate (mL/min)
Preoperative	1.12 ± 0.31	1.15 ± 0.38	0.621
24 h	0.95 ± 0.32	1.03 ± 0.34	0.168
48 h	0.82 ± 0.29	0.95 ± 0.28	0.010
72 h	0.86 ± 0.25	1.05 ± 0.37	0.001
eGFR [mL/(min/1.73 m2)]
Preoperative	85.76 ± 22.46	86.35 ± 21.27	0.877
24 h	78.43 ± 9.12	82.11 ± 10.23	0.030
48 h	76.82 ± 8.55	83.27 ± 10.13	0.001
72 h	77.432 ± 5.120	85.38 ± 7.22	0.001

rhBNP: Recombinant human brain natriuretic peptide.