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©The Author(s) 2022.
World J Clin Cases. Nov 26, 2022; 10(33): 12089-12103
Published online Nov 26, 2022. doi: 10.12998/wjcc.v10.i33.12089
Published online Nov 26, 2022. doi: 10.12998/wjcc.v10.i33.12089
Table 4 Univariate and multivariate Cox regression analyses of pyruvate dehydrogenase A1 expression and the clinicopathological factors in the esophagus cancer patients
| Variables | Overall survival | Progression-free survival | ||
| HR (95%CI of HR) | P value | HR (95%CI of HR) | P value | |
| PDHA1 low | 1.00 (Reference) | 1.00 (Reference) | ||
| UVA PDHA1 high | 2.34 (1.42-3.87) | 0.0009 | 1.51 (0.95-2.38) | 0.08 |
| MVA PDHA1 high | 1.67 (1.03-2.73) | 0.0386 | ||
| Age ≤ 65 | 1.00 (Reference) | 1.00 (Reference) | ||
| Age > 65 | 0.81 (0.47-1.41) | 0.46 | 0.97 (0.60-1.55) | 0.89 |
| Sex, Female | 1.00 (Reference) | 1.00 (Reference) | ||
| UVA Male | 2.12 (0.84-5.34) | 0.11 | 2.97 (1.19-7.39) | 0.02 |
| MVA Male | 2.27 (0.90- 5.73) | 0.08 | ||
| Pathological types, adenocarcinoma | 1.00 (Reference) | 1.00 (Reference) | ||
| SCC | 0.81 (0.47-1.39) | 0.45 | 1.11 (0.70-1.77) | 0.66 |
| AJCC stage I, II | 1.00 (Reference) | 1.00 (Reference) | ||
| UVA AJCC stage III, IV | 2.53 (1.76-3.64) | 5.86 × 10-7 | 1.98 (1.46-2.67) | 9.48 × 10-6 |
| MVA AJCC stage III, IV | 2.30 (1.58-3.35) | 1.46 × 10-5 | 1.86 (1.37-2.52) | 6.98 × 10-5 |
- Citation: Xu H, Du QC, Wang XY, Zhou L, Wang J, Ma YY, Liu MY, Yu H. Comprehensive analysis of the relationship between cuproptosis-related genes and esophageal cancer prognosis. World J Clin Cases 2022; 10(33): 12089-12103
- URL: https://www.wjgnet.com/2307-8960/full/v10/i33/12089.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v10.i33.12089