T-cell immunoglobulin mucin molecule-3, transformation growth factor β, and chemokine-12 and the prognostic status of diffuse large B-cell lymphoma

Table 4 Multivariate Cox analysis affecting patient outcomes

Variables	r	SD	Wald	P value	OR	95%CI
Bone marrow infiltration	0.820	0.251	10.686	0.001	2.270	1.472-3.934
Clinical stages	1.537	0.419	13.478	< 0.001	4.649	2.940-15.168
IPI score	0.949	0.273	12.074	0.001	2.582	1.626-4.741
Tim-3 expression	1.027	0.279	13.540	< 0.001	2.792	1.744-5.207
TGF-β expression	1.195	0.360	11.010	0.001	3.304	1.954-8.019
CXCL12 expression	1.305	0.401	10.600	0.001	3.688	2.102-10.117

r: Regression coefficient; OR: Odds ratio; CI: Confidence interval; IPI: International Prognostic Index; Tim-3: T-cell immunoglobulin mucin molecule-3; TGF-β: Transforming growth factor β; CXCL12: Chemokine 12; DLBCL: Diffuse large B-cell lymphoma.