Quality of life and symptom distress after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

Table 2 Descriptive data of the European Organization for Research and Treatment of Cancer Quality of Life-Core 30-item and MD Anderson symptom inventory questionnaires, n = 58

Scales	Items	S1 (n = 58)	S2 (n = 58)	S3 (n = 55)	P value1	The pairwise comparison between S1/S21	The pairwise comparison between S2/S31	The pairwise comparison between S1/S31
QLQ-C30	30	53.5 (8.6)	57.3 (9.8)	54.0 (9.8)	0.066	0.08	0.152	0.96
Global health status	2	60.3 (19.4)	56.6 (15.4)	64.4 (17.5)	0.065	0.486	0.051	0.439
Functional scales	15
Physical functioning	5	82.2 (15.0)	70.5 (19.0)	80.6 (18.2)	0.001	0.001	0.007	0.881
Role functioning	2	78.7 (23.9)	64.1 (23.9)	76.4 (25.2)	0.003	0.004	0.022	0.863
Emotional functioning	4	74.6 (14.8)	78.3 (17.2)	80.6 (17.8)	0.152	0.449	0.743	0.134
Cognitive functioning	2	84.8 (17.2)	85.3 (13.3)	87.3 (18.4)	0.7	0.981	0.807	0.697
Social functioning	2	76.4 (25.8)	74.7 (22.8)	82.7 (20.0)	0.155	0.914	0.157	0.317
Symptom scales	13
Fatigue	3	26.2 (16.5)	37.5 (21.7)	32.1 (16.9)	0.005	0.004	0.269	0.215
Pain	2	14.9 (18.4)	27.0 (19.5)	14.2 (17.7)	< 0.001	0.002	0.001	0.978
Nausea and vomiting	2	9.8 (21.2)	8.0 (16.0)	12.7 (19.0)	0.413	0.875	0.386	0.682
Dyspnea	1	12.1 (17.3)	17.8 (20.0)	9.7 (15.3)	0.044	0.189	0.041	0.756
Insomnia	1	23.6 (27.2)	24.1 (26.3)	21.2 (22.6)	0.813	0.992	0.815	0.876
Appetite loss	1	21.3 (23.9)	27.6 (28.0)	27.3 (22.3)	0.311	0.361	0.998	0.408
Constipation	1	12.1 (23.9)	12.1 (20.4)	17.6 (25.5)	0.357	1	0.424	0.424
Diarrhea	1	12.6 (19.6)	11.5 (19.3)	17.0 (21.2)	0.314	0.949	0.316	0.485
Financial difficulties	1	21.3 (24.7)	21.3 (26.3)	17.0 (23.0)	0.571	1	0.627	0.627
MDASI-T	19
Symptom severity	13	14.8 (12.5)	16.8 (12.8)	15.3 (15.2)	0.726	0.722	0.836	0.98
Degree of interference with life	6	9.6 (9.5)	10.7 (10.0)	7.5 (8.6)	0.186	0.791	0.166	0.468

¹P values were calculated using one-way analysis of variance (ANOVA). Bold: P < 0.05.

MDASI-T: MD Anderson Symptom Inventory - Traditional version; QLQ-C30: Quality of Life-Core 30-item. S1: The first visit before CRS/HIPEC; S2: The second visit at the first outpatient follow-up after CRS/HIPEC; S3: The third visit at the outpatient visit 3 months after CRS/HIPEC. The data are presented as the mean and standard deviation of the scores (in parentheses).