Endoscopic submucosal tunnel dissection for early esophageal squamous cell carcinoma in patients with cirrhosis: A propensity score analysis

Table 3 Endoscopic efficacy and safety in patients with or without liver cirrhosis underwent endoscopic submucosal tunnel dissection

Clinical data	Cirrhosis (n = 25)	Noncirrhosis (n = 75)	P value
Number of tunnels			0.430
Single tunnel	17 (68.0)	57 (76.0)
Multiple tunnels	8 (32.0)	18 (24.0)
R0 resection	22 (88.0)	65 (86.7)	1.000
Curative resection	19 (76.0)	57 (76.0)	1.000
Dissection speed, mm²/min (SD)	24.5 (11.6)	21(11.8)	0.200
Intraoperative bleeding	12 (48.0)	26 (34.7)	0.234
30-d post-ESTD bleeding	2 (8.0)	0 (0)	0.099
Muscular injury	5 (20.0)	23 (30.7)	0.304
Prednisone used post-ESTD	5 (20.0)	18 (24.0)	0.681
Stenosis	2 (8.0)	12 (16.0)	0.506
Perforation	0 (0)	3 (4.0)	0.735
Post-ESTD fever	11 (44.0)	21 (28.0)	0.137
Post-ESTD pneumonia	2 (8.0)	16 (21.3)	0.229
Hospitalization, day (SD)	14.9 (7.5)	10.3 (4.5)	0.007
Post-ESTD duration, d (SD)	6.5 (2.9)	6.1 (2.9)	0.523
Hospitalization costs, $ (SD)	4985.9 (1815.7)	4083.8 (759.0)	0.023
Median follow-up time, months	45	39	0.430
Local Recurrence	1 (4)	3 (4)	1.000
OS	17 (68.0)	71 (94.7)	0.001
DSS	24 (96.0)	75 (100.0)	0.075
RFS	24 (96.0)	72 (96.0)	0.8196

Values are mean, median, n, or n (%). ESTD: Endoscopic submucosal tunnel dissection; OS: Overall survival; DSS: Disease-specific survival; RFS: Recurrence-free survival; SD: Standard deviation.