Screening of traditional Chinese medicine monomers as ribonucleotide reductase M2 inhibitors for tumor treatment

doi:10.12998/wjcc.v10.i31.11299

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Nov 6, 2022 (publication date) through Sep 1, 2024

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Clinical and Translational Research

World J Clin Cases. Nov 6, 2022; 10(31): 11299-11312
Published online Nov 6, 2022. doi: 10.12998/wjcc.v10.i31.11299

Table 2 The traditional Chinese medicine monomers confirmed or predicted having ribonucleotide reductase M2 inhibition in tumors

Name	In vivo study	In vitro study	Bioinformatics analysis
Berberine	-	Non-small cell lung cancer	Breast cancer
Ursolic acid	-	-	Hepatoma, Colon cancer
Gambogic acid	Pancreatic cancer	Pancreatic cancer	-
Cinobufagin	Endometrial carcinoma	Endometrial carcinoma	-
Quercetin	-	-	Hepatoma, Colon cancer
Daphnetin	-	-	-
Osalmide	Esophageal Cancer, Multiple myeloma, Hepatocellular carcinoma, Diffuse large B-cell lymphoma	Esophageal Cancer, Multiple myeloma, Hepatocellular carcinoma, Diffuse large B-cell lymphoma	Multiple myeloma, Hepatocellular carcinoma

Citation: Qin YY, Feng S, Zhang XD, Peng B. Screening of traditional Chinese medicine monomers as ribonucleotide reductase M2 inhibitors for tumor treatment. World J Clin Cases 2022; 10(31): 11299-11312
URL: https://www.wjgnet.com/2307-8960/full/v10/i31/11299.htm
DOI: https://dx.doi.org/10.12998/wjcc.v10.i31.11299