Hypophysitis induced by anti-programmed cell death protein 1 immunotherapy in non-small cell lung cancer: Three case reports

Figure 1 Pituitary magnetic resonance imaging and laboratory examination results in case 1. A: The pituitary was normal before starting immunotherapy (November 30, 2019); B: Pituitary enlargement was not found at the onset of immune-related hypophysitis (July 26, 2020); C: The pituitary was normal after steroid treatment (December 18, 2020); D: The levels of adrenocorticotropic hormone and cortisol; E: The levels of thyroid stimulating hormone and free thyroxine. ACTH: Adrenocorticotropic hormone; TSH: Thyroid stimulating hormone; FT4: Free thyroxine.