Hyperthermic intraperitoneal chemotherapy and colorectal cancer: From physiology to surgery

doi:10.12998/wjcc.v10.i30.10852

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Oct 26, 2022 (publication date) through Nov 5, 2024

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World Journal of Clinical Cases

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World J Clin Cases. Oct 26, 2022; 10(30): 10852-10861
Published online Oct 26, 2022. doi: 10.12998/wjcc.v10.i30.10852

Table 1 List of clinical studies with phases, correlated institutions and principal investigators (Clinicaltrials.gov or clinicaltrialsregister.eu; the list below describes the brief titles of the ended clinical trials)

Phase	Institution/Group	Country	Author/ClinicalTrials.gov ID	Year beginning
II	Fudan University	China	Guoxiang Cai/NCT02965248	November 2016
III	Zhejiang University	China	Ding Ke-Feng/NCT02179489	October 2014
II	Wuhan University	China	Bin Xiong/NCT02830139¹	July 2016
II/III	Catharina, Ziekenhuis, Eindhoven	Netherlands	Koen Rovers/NCT02758951	June 2017
III	Academisch Medisch Centrum-Universiteit van Amsterdam	Netherlands	P.J. Tanis/NCT02231086	March 2015
III	Universitair Medisch Centrum Groningen	Netherlands	NACHO trial /2010-020787-37	January 2013
II	University Hospital, Ghent	Belgium	Wim P Ceelen/NCT02399410	December 2015
II	University Hospital, Ghent	Belgium	Trial Bureau/2012-000701-77²	May 2012
II	University Hospital, Ghent	Belgium	Bimetra Clinics/2014-000882-34³	June 2014
III	Gustav Roussy, Cancer Campus, Grand Paris	France	Diane GOERE/NCT01226394	April 2010
I/II	Hospices Civils de Lyon	France	Benoit You/NCT02866903⁴	May 2017
III	UNICANCER	France/Spain	BEATA JUZYNA/2006-006175-20	December 2012
III	University of Roma La Sapienza	Italy	P.Sammartino/NCT02974556	March 2019
III	Maimonides Biomedical Research Institute of Cordoba	Spain	Alvaro Arjona Sanchez /NCT02614534	November 2015

¹Radical colorectal resection and hyperthermic intraperitoneal chemotherapy in locally advanced colorectal cancer.

²Cytoreduction followed by normothermic vs hyperthermic intraperitoneal intraoperative chemoperfusion: A phase II study in peritoneal carcinomatosis.

³Catheter based adjuvant intraperitoneal chemotherapy for carcinomatosis.

⁴IPOXA, phase I/II dose escalation trial aiming to evaluate the safety of intraperitoneal oxaliplatin in association with systemic FOLFIRI bevacizumab chemotherapy in patients with peritoneal carcinosis of colorectal origin and uncertain resectability.

Citation: Ammerata G, Filippo R, Laface C, Memeo R, Solaini L, Cavaliere D, Navarra G, Ranieri G, Currò G, Ammendola M. Hyperthermic intraperitoneal chemotherapy and colorectal cancer: From physiology to surgery. World J Clin Cases 2022; 10(30): 10852-10861
URL: https://www.wjgnet.com/2307-8960/full/v10/i30/10852.htm
DOI: https://dx.doi.org/10.12998/wjcc.v10.i30.10852