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World J Clin Cases. Jan 21, 2022; 10(3): 777-789
Published online Jan 21, 2022. doi: 10.12998/wjcc.v10.i3.777
Figure 2
Figure 2 Pathophysiology of anemia and role of hepcidin. Fe2+: Ferrous iron; Fe3+: Ferric iron; Dyctb: Duodenal cytochrome B; DMT-1: Divalentmetaltransporter-1; FPN: Ferroportin; Tf: Transferrin; Tfr: Transferrin receptor; IL6: Interleukin 6; IL6r: Interleukin 6 receptor; STAT-3: Signaltransducer and activator of transcription proteins 3; HFE: Human homeostatic iron regulator; HIF: Hypoxia inducible factor.