Dynamic monitoring of carcinoembryonic antigen, CA19-9 and inflammation-based indices in patients with advanced colorectal cancer undergoing chemotherapy

Table 5 Binary logistic regression, and univariate and multivariate analyses

Markers	Univariate logistic regression	Multivariate logistic regression
CEA	1.005 (1.002-1.008), P < 0.001	1.004 (1.000-1.007); P = 0.044
CA19-9	1.005 (1.001-1.008), P = 0.015	1.001 (0,998-1.004), P > 0.05
NLR	1.011 (1.004-1.018), P = 0.001	1.015 (0.996-1.034), P > 0.05
PLR	1.009 (1.001-1.018), P = 0.034	1.003 (0.986-1.021), P > 0.05
LMR	1.000 (0.993-1.007), P > 0.05
SII	1.006 (1.002- 1.010), P = 0.004	0.997 (0.985-1.009), P > 0.05

Dynamic change in markers and dichotomous response evaluation criteria in solid tumour 1.1 outcomes progressive disease (PD) and non-PD (disease control). Data are presented as Exp(B) with 95%CI for EXP(B). CEA: Carcinoembryonic antigen; CA19-9: Carbohydrate antigen; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; LMR: Lymphocyte-to-monocyte ratio; SII: Systemic immune-inflammation index.