Relationship of familial cytochrome P450 4V2 gene mutation with liver cirrhosis: A case report and review of the literature

Table 1 Changes of liver function indicators in the index patient

Date	ALT, U/L	AST, U/L	TBIL, μmol/L	DBIL, μmol/L	IBIL μmol/L	GGT, U/L	ALP, U/L	ALB, g/L	GLO, g/L
	Ref: 0-40	Ref: 0-34	Ref: 5.1-19.0	Ref: 1.7-6.8	Ref: 1.7-13.2	Ref: 0-50	Ref: 40-150	Ref: 38-51	Ref: 20-30
2020-10-14	89.9↑	259.6↑	94.13↑	44.45↑	49.68↑	40.70	178.7↑	25.30↓	51.7↑
2020-10-20	58.9↑	164.7↑	90.92↑	39.89↑	51.03↑	35.77	158.5↑	33.03↓	43.0↑
2021-01-14	86.9↑	182.5↑	109.91↑	60.62↑	49.28↑	37.60	69.9	21.20↓	55.3↑
2021-01-26	61.0↑	159.2↑	71.90↑	44.26↑	27.64↑	28.60	87.5	27.70↓	30.0
2021-04-18	63.7↑	204.4↑	102.32↑	68.26↑	34.06↑	31.40	117.4	24.00↓	35.6↑
2021-04-25	46.2↑	151.8↑	79.40↑	53.25↑	26.15↑	28.80	105.3	30.60↓	32.3↑
2021-07-14	53.3↑	164.7↑	95.24↑	65.73↑	29.51↑	34.00	116.7	25.30↓	34.7↑
2021-07-25	36.72	113.5↑	80.00↑	57.63↑	22.37↑	-	-	33.78↓	27.7

Here and below: Bold number with upward arrow, abnormally high; bold number with downward arrow, abnormally low. ALT: Alanine transaminase; AST: Aspartate aminotransferase; TBIL: Total bilirubin; DBIL: Direct bilirubin; IBIL: Indirect bilirubin; GGT: Gamma glutamyl transpeptidase; ALP: Alkaline phosphatase; ALB: Albumin; GLO: Globulin.