Effects of targeted-edited oncogenic insulin-like growth factor-1 receptor with specific-sgRNA on biological behaviors of HepG2 cells

Table 3 Levels of insulin-like growth factor-1 receptor or P-glycoprotein expression in sera of patients with liver diseases

Group	n	IGF-1R (pg/mL)	P-gp (ng/mL)
HCC	93	758.6 ± 126.4	11.6 ± 5.1
Liver cirrhosis	40	521.4 ± 78.3	7.3 ± 6.3
Chronic hepatitis	40	456.8 ± 82.1	3.7 ± 1.4
Health control	40	421.8 ± 58.6	1.0 ± 0.5
F value		154.501	66.182
q value1		0.689	0.487
P value		< 0.001	< 0.001

¹Compared between hepatocellular carcinoma group and liver cirrhosis group. HCC: Hepatocellular carcinoma; IGF-1R: Insulin-like growth factor-1 receptor; P-gp: P-glyco protein.