Effects of targeted-edited oncogenic insulin-like growth factor-1 receptor with specific-sgRNA on biological behaviors of HepG2 cells

Table 1 Positive rates of insulin-like growth factor-1 receptor and P-glyco protein expression and immunohistochemistry score in hepatocellular carcinoma tissues

Group	n	IHC		χ2 value	P value	IHC score				Z value	P value
		Neg.	Pos.			0	1	2	3
IGF-IR				63.947	< 0.001					9.682	< 0.001
HCC	93	6	87			6	10	67	10
Non-Ca	93	59	34			59	25	9	0
P-gp				58.448	< 0.001					8.941	< 0.001
HCC	93	11	82			11	14	57	12
Non-Ca	93	68	25			68	22	2	0

HCC: Hepatocellular carcinoma; Non-Ca: Non-cancerous tissues; IHC: Immunohistochemistry; IGF-IR: Insulin-like growth factor-1 receptor; Neg: Negative IGF-1R expression; P-gp: P-glyco protein; Pos: Positive IGF-1R expression.