Drug-induced lung injury caused by acetaminophen in a Japanese woman: A case report

Table 2 Clinical characteristics of patients with reported acetaminophen-induced lung injury

Case	Sex	Age (years)	Ethnicity	Drugs	Symptoms	Time between drug use and presentation (d)	Time between initial diagnosis and drug discontinuation (d)	Treatment	Outcome	Ref.
1	Female	20	Japanese	Acetaminophen (Norshin®)	Fever, cough, and dyspnea	2	0	Drug discontinuation; Corticosteroids	Disease resolution	Kitaguchi et al[10], 1992
2	Female	63	Japanese	Acetaminophen (Caronal®)	Cough and dyspnea	8	10	Drug discontinuation; Corticosteroids	Disease resolution	Kudeken et al[11], 1993
3	Male	45	Japanese	Acetaminophen (PL Combination Granules®)	Fever, cough, and diarrhea	4	0	Drug discontinuation	Disease resolution	Nakatsumi et al[12], 1994
4	Male	75	Japanese	Acetaminophen (Pabron gold®/Pabron S®)	Fever and dyspnea	3	0	Drug discontinuation; Corticosteroids	Disease resolution	Nomura et al[13], 1997
5	Male	57	Japanese	Acetaminophen (PL Combination Granules® /Shin Lulu A Tablets®)	Fever, cough, and dyspnea	11	8 months	Drug discontinuation; Corticosteroids	Respiration and disease resolution	Kawano et al[14], 1997
6	Female	64	Japanese	Acetaminophen (Caronal®)	Fever, cough, and dyspnea	19	8	Drug discontinuation; Corticosteroids	Disease resolution	Akashi et al[15], 1997
7	Female	70	Japanese	Acetaminophen (Caronal®)	Fever, cough, and dyspnea	6	5	Drug discontinuation; Corticosteroids	Disease resolution	Nakajima et al[16], 1998
8	Female	49	Japanese	Acetaminophen (Benza Block SP®)	Fever and dyspnea	5	5	Drug discontinuation; Corticosteroids	Disease resolution	Nakajima et al[16], 1998
9	Male	72	Japanese	Acetaminophen (PL Combination Granules®)	Fever and dyspnea	1	0	Drug discontinuation; Corticosteroids	Respiration and Disease resolution	Ikeuchi et al[17], 2000
10	Male	31	Japanese	Acetaminophen (PL Combination Granules®)	Fever and cough	13	31	Drug discontinuation	disease resolution	Hiramatsu et al[18], 2002
11	Female	68	Japanese	Acetaminophen (PL Combination Granules®)	Fever, cough, and dyspnea	6	0	Drug discontinuation; Corticosteroids, Cyclosporine	Disease resolution	Nakayama et al[19], 2006
12	Female	41	Japanese	Acetaminophen (Ibuprofen®/Caronal®)	Fever, cough, and dyspnea	3	0	Drug discontinuation; Corticosteroids	Disease resolution	Anan et al[20], 2009
13	Female	84	Japanese	Acetaminophen (Shin Lulu A Tablets s®)	Fever, cough, and dyspnea	5	0	Drug discontinuation; Corticosteroids	Disease resolution	Kato et al[21], 2010
14	Female	80	Japanese	Acetaminophen (Caronal®)	Fever and dyspnea	15	0	Drug discontinuation; Corticosteroids	Disease resolution	Sasaki et al[22], 2014
15	Female	68	Caucasian	Acetaminophen (Caronal®)	Cough and dyspnea	Months	Not specified	Drug discontinuation	Disease resolution	Saint-Pierre et al[23], 2016
16	Female	79	Japanese	Acetaminophen (Caronal®)	Dyspnea	2	0	Drug discontinuation; Corticosteroids	Disease resolution	Ueda et al[24], 2019
Present case	Female	35	Japanese	Acetaminophen (Caronal®)	Fever	4	11	Drug discontinuation	Disease resolution	-