Development and validation of an epithelial–mesenchymal transition-related gene signature for predicting prognosis

Figure 4 Prognostic analysis of the 7 epithelial-mesenchymal transition-associated gene signature model in the derivation cohort. A: The median value and distribution of the risk scores. B: The results of principal component analysis (PCA) indicated that patients with lung adenocarcinoma (LUAD) were significantly distributed in two regions according to the risk score; C: The results of t-distributed stochastic neighbor embedding (t-SNE) analysis suggested that LUAD patients clustered in two different regions; D: The distributions of the overall survival (OS) status; the results showed that patients with a higher risk score had shorter survival times than those with lower risk scores; E: Kaplan-Meier analysis of OS for patients in the high-risk group and the low-risk group in the derivation cohort. F: The area under the curve (AUC) of the time-dependent receiver operator characteristic curve (ROC) verified the predictive performance of the prognostic risk score in the derivation cohort.