Case Report
Copyright ©The Author(s) 2022.
World J Clin Cases. Sep 16, 2022; 10(26): 9368-9377
Published online Sep 16, 2022. doi: 10.12998/wjcc.v10.i26.9368
Table 1 Antithrombotic therapy in the primary prevention settings of Kawasaki disease
Agent
Indication
Dose
Monitoring
Mechanism of action
AspirinInitial therapy for prevention of thrombosis.(Z score ≥ 2.5)3-5 mg/kg/day-Cyclooxygenase-1 inhibitor
ClopidogrelResistance to aspirin or aspirin allergy. Dual-antiplatelet therapy for thromboprophylaxis0.2-1.0 mg/kg/day-P2Y12 inhibitor
Prasugrel/ticagrelorNANANAP2Y12 inhibitor
WarfarinThromboprophylaxis for large or giant aneurysm. (Z score > 10)INR 2-3Vitamin K antagonist
LMWHThromboprophylaxis for large or giant aneurysm.(Z score > 10)Dosage varies according to age and agent-Active antithrombin III