Evaluation of high-risk factors and the diagnostic value of alpha-fetoprotein in the stratification of primary liver cancer

Table 9 Evaluation of the four indicators for the diagnosis of Barcelona Clinic Liver Cancer stage A liver cancer alone and in combination

Diagnostic indicators	AUC	Sensitivity, %	Specificity, %	Std.Error	95%CI	Z	P value
AFP	0.593	30.19	96.17	0.0481	(0.550, 0.634)	1.93	0.0538
CEA	0.611	32.08	96.00	0.0462	(0.551, 0.669)	1.197	0.2313
CA-199	0.608	75.47	42.86	0.0429	(0.548, 0.666)	2.511	0.0121
GGT	0.743	60.38	78.22	0.0380	(0.688, 0.794)	6.409	< 0.0001
Combined diagnosis	0.843	66.04	91.96	0.0319	(0.794, 0.883)	10.738	< 0.0001

AUC: Area under the curve; AFP: Alpha-fetoprotein; CEA: Carcinoembryonic antigen; CA 19-9: Carbohydrate antigen 19-9; GGT: Gamma-glutamyl transferase.