Evaluation of high-risk factors and the diagnostic value of alpha-fetoprotein in the stratification of primary liver cancer

Table 3 Influence of high-risk factors on primary liver cancer stratified by pathological classification of tumor size

Factors	Criterion: Pathological classification of tumor size					Statistics	P value
	Small	Medium	Large	Massive	Diffuse
Male (%)	30 (68.2)	17 (70.8)	30 (66.7)	22 (75.9)	117 (80.1)	5.05	0.283
Age (yr)	62.86 ± 9.03	59.45 ± 10.43	61.86 ± 8.86	57.79 ± 11.69	63.03 ± 11.75	1.75	0.139
History of smoking (%)	9 (20.5)	9 (37.5)	12 (26.7)	12 (41.4)	55 (37.4)	6.29	0.179
History of drinking (%)	10 (22.7)	8 (33.3)	14 (31.1)	11 (37.9)	57 (38.8)	4.28	0.370
HBsAg (+) (%)	20 (45.5)	14 (58.3)	23 (51.1)	14 (48.3)	83 (56.5)	2.30	0.680
HCV-Ag (+) (%)	3 (6.8)	1 (4.2)	4 (8.9)	2 (6.9)	7 (4.8)	1.32	0.858
Cirrhosis (%)	31 (70.5)	17 (70.0)	20 (44.4)	10 (34.5)a	74 (50.3)	14.15	0.007
Non-alcoholic fatty liver (%)	10 (22.7)	7 (29.2)	7 (15.6)	7 (24.1)	36 (24.5)	2.11	0.715

^aCompared with “Small”, P < 0.005. HBsAg: Hepatitis B virus antigen; HCV: Hepatitis C virus.