Role of octreotide in small bowel bleeding

Table 1 Summary of clinical trials assessing long-acting somatostatin analogs in treating angiodysplasia patients.

Ref.	Year of publication	Number of patients	Number of transfusions before treatment	Number of transfusions after treatments	bP	Hemoglobin levels before treatment (g/dL)	Hemoglobin levels after treatment (g/dL)	cP	Follow-up duration
Nardone et al[30]	1999	17	8.8	1.5	< 0.0005	5.7	11.1	< 0.0005	6 mo
Scaglione et al[31]	2007	13	N/A	N/A	< 0.003	13	7	< 0.002	33 mo
Bon et al[32]	2012	15	2	10	< 0.001	10	7	< 0.001	12 mo
Holleran et al[33]	2016	24	17 patients1 1.35	0.35	< 0.001	9.19	11.35	< 0.0027	8.8 mo
			7 patients1 2.25	1.07	< 0.002

^bP value for reduction of transfusions.

^cP value for reduction of hemoglobin levels.

¹{Loyaga-Rendon, 2015 #34}: 17 patients (70%) did not require blood transfusions while on treatment. However, 7 patients still required blood transfusions.

N/A: Not applicable; SD: Standard deviation.