Quantitative differentiation of malignant and benign thyroid nodules with multi-parameter diffusion-weighted imaging

doi:10.12998/wjcc.v10.i24.8587

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Aug 26, 2022; 10(24): 8587-8598
Published online Aug 26, 2022. doi: 10.12998/wjcc.v10.i24.8587

Table 1 Interreader reproducibility of measurement of diffusion parameters of thyroid nodules

Diffusion parameter	ICC	95%CI
Mono-exponential
ADC_{(0 and 1000)}	0.944	(0.852, 0.979)
ADC_{(0 to 1000)}	0.938	(0.898, 0.962)
ADC_{(0 and 2000)}	0.904	(0.844, 0.941)
ADC_{(0 to 2000)}	0.942	(0.905, 0.962)
Biexponential
D	0.949	(0.921, 0.967)
D*	0.935	(0.900, 0.958)
f	0.897	(0.844, 0.933)
stretched exponential
DDC	0.994	(0.990, 0.996)
α	0.973	(0.958, 0.983)
Kurtosis DWI
Dapp	0.787	(0.685, 0.859)
Kapp	0.855	(0.782, 0.905)

ADC: Apparent diffusion coefficient; DWI: Diffusion-weighted imaging; D: Slow diffusion coefficient; D*: Fast diffusion coefficient; f: Fraction of fast diffusion; DDC: Distributed diffusion coefficient; ICC: Intraclass correlation; α: Anomalous exponent term; Dapp: Mean diffusivity; Kapp: Mean kurtosis.

Citation: Zhu X, Wang J, Wang YC, Zhu ZF, Tang J, Wen XW, Fang Y, Han J. Quantitative differentiation of malignant and benign thyroid nodules with multi-parameter diffusion-weighted imaging. World J Clin Cases 2022; 10(24): 8587-8598
URL: https://www.wjgnet.com/2307-8960/full/v10/i24/8587.htm
DOI: https://dx.doi.org/10.12998/wjcc.v10.i24.8587