Effects of propofol combined with lidocaine on hemodynamics, serum adrenocorticotropic hormone, interleukin-6, and cortisol in children

Table 1 Comparison of hemodynamic indexes of two groups of children (mean ± SD)

Groups	T0	T1	T2	T3
HR (times/min)
A group	113.6 ± 8.2	120.5 ± 8.0	118.9 ± 7.5	115.5 ± 8.4
B group	115.0 ± 9.0	126.1 ± 7.4	125.0 ± 8.3	116.8 ± 8.0
F value	F1 = 13.025, F2 = 15.776, F3 = 8.169
P value	P1 = 0.000, P2 = 0.000, P3 = 0.000
MAP (mmHg)
A group	85.2 ± 6.9	92.7 ± 5.5	92.0 ± 5.9	87.0 ± 5.3
B group	84.8 ± 6.5	96.0 ± 6.2	95.1 ± 6.8	89.1 ± 6.5
F value	F1 = 9.881, F2 = 13.764, F3 = 6.990
P value	P1 = 0.000, P2 = 0.000, P3 = 0.000
SpO2 (%)
A group	98.2 ± 0.6	97.7 ± 0.7	97.8 ± 0.6	98.0 ± 0.5
B group	98.3 ± 0.7	97.6 ± 0.6	97.9 ± 0.8	97.8 ± 0.7
F value	F1 = 2.514, F2 = 6.395, F3 = 1.552
P value	P1 = 0.168, P2 = 0.000, P3 = 0.351

F1 and P1 are between groups, F2 and P2 are time effect, F3 and P3 are interaction. HR: Heart rate; MAP: mean arterial pressure; SpO₂: Arterial oxygen saturation.