Short-term prognostic factors for hepatitis B virus-related acute-on-chronic liver failure

doi:10.12998/wjcc.v10.i23.8186

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 10, Issue 23

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (3623)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-1) series, Tables (1-4) series.

Item

Count

PDF

178

WORD

HTML

1817

Figures (1-1)

326

Tables (1-4)

318

Sum=2682

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

279

Download

662

Sum=941

Aug 16, 2022 (publication date) through Dec 1, 2024

Times Cited of This Article

Times Cited (4)

Journal Information of This Article

Publication Name

World Journal of Clinical Cases

ISSN

2307-8960

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Observational Study

World J Clin Cases. Aug 16, 2022; 10(23): 8186-8195
Published online Aug 16, 2022. doi: 10.12998/wjcc.v10.i23.8186

Table 1 Demographic and clinical characteristics

	Survival group (n = 157)	Death group (n = 50)	P value
Age (yr)	40 (32, 48)	51(39, 55)	0.000
Gender (male, %)	130/157, 82.8	42/50, 84.0	0.844
Classification of liver failure (%)			0.006
A	116/157, 73.89	29/50, 58.00
B	92/157, 58.60	16/50, 32.00
C	2/157, 1.27	5/50, 10.00
Stage of liver failure (%)			0.000
Early	101/157, 64.33	5/50, 10.00
Middle	42/157, 26.75	13/50, 26.00
Late	14/157, 8.92	32/50, 64.00
Complications (%)
Pulmonary infection	39/157, 24.84	24/50, 48.00	0.003
Hepatic encephalopathy	10/157, 6.37	23/50, 46.00	0.000
Spontaneous bacterial peritonitis	10/157, 6.37	11/50, 22.00	0.005
Hepatorenal syndrome	0/157, 0	4/50, 8.00	0.003
Upper gastrointestinal hemorrhage	2/157, 1.27	6/50, 12.00	0.003
PLT (10⁹/L)	128 (102, 154.50)	103 (87.50, 153)	0.044
ALB (g/dL)	3.28 ± 0.50	3.21 ± 0.53	0.381
Tbil (mg/dL)	13.55 (9.59, 19.88)	17.19 (12.36, 25.65)	0.011
ALT (U/L)	948.50 (400, 1984.7)	838.8 (331.40, 1705.78)	0.626
AST (U/L)	687.90 (273.85, 1258.50)	721.50 (252.50, 1554.35)	0.800
CHE (U/L)	4359 (3288, 5429)	3898 (2786.75, 5029.50)	0.197
Glu (mmol/L)	4.26 (3.65, 5.23)	4.64 (3.73, 5.75)	0.276
BUN (mg/dL)	9.08 (7.21, 12.30)	10.97 (8.42, 15.16)	0.014
Cr (mg/dL)	0.73 (0.61, 0.84)	0.76 (0.62, 0.94)	0.309
Na (mmol/L)	136.30 (134.30, 138.00)	135.22 (132.48, 138.33)	0.172
NLR	2.66 (1.89, 4.05)	4.00 (2.42, 6.43)	0.000
INR	1.83 (1.65, 2.13)	2.23 (1.93, 3.18)	0.000
HBsAg (log₁₀IU/L)	3.70 (3.31, 3.91)	3.23 (2.65, 3.74)	0.001
HBeAg positive (%)	89/157 (56.70)	16/50 (32.00)	0.002
HBV-DNA (log₁₀IU/L)	6.34 (5.14, 7.46)	6.39 (4.87, 7.82)	0.698
AFP (ng/mL)	63.15 (15.35, 204)	16.18 (6.79, 48.33)	0.000
GP73 (ng/mL)	237.92 (208.84, 309.79)	305.83 (215.32, 366.49)	0.003

AFP: Alpha-fetoprotein; ALB: Albumin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; BUN: Blood urea nitrogen; CHE: Cholinesterase; Cr: Creatinine; Glu: Blood glucose; GP73: Golgi protein 73; HBV: Hepatitis B virus; INR: International normalized ratio; NLR: Neutrophil-to-lymphocyte ratio; PLT: Platelet count; Tbil: Total bilirubin.

Citation: Ye QX, Huang JF, Xu ZJ, Yan YY, Yan Y, Liu LG. Short-term prognostic factors for hepatitis B virus-related acute-on-chronic liver failure. World J Clin Cases 2022; 10(23): 8186-8195
URL: https://www.wjgnet.com/2307-8960/full/v10/i23/8186.htm
DOI: https://dx.doi.org/10.12998/wjcc.v10.i23.8186