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©The Author(s) 2022.
World J Clin Cases. Aug 16, 2022; 10(23): 8170-8185
Published online Aug 16, 2022. doi: 10.12998/wjcc.v10.i23.8170
Published online Aug 16, 2022. doi: 10.12998/wjcc.v10.i23.8170
Variables | Age group (yr) | Group A (famotidine) | Group B (control) | ||||||||
1-10 d | 11-20 d | 21-30 d | > 31 d | Total | 1-10 d | 11-20 d | 21-30 d | > 31 d | Total | ||
Duration of hospital stay (recovered cases), group A (n = 78), group B (n = 73) | 11-20 | 0 | 2 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 |
21-30 | 0 | 1 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | |
31-40 | 3 | 4 | 1 | 0 | 8 | 8 | 8 | 0 | 0 | 16 | |
41-50 | 4 | 5 | 0 | 0 | 9 | 0 | 8 | 0 | 0 | 8 | |
51-60 | 13 | 8 | 3 | 0 | 24 | 4 | 8 | 4 | 0 | 16 | |
61-70 | 5 | 13 | 1 | 0 | 19 | 0 | 16 | 4 | 0 | 20 | |
71-80 | 5 | 4 | 1 | 0 | 10 | 1 | 4 | 4 | 0 | 9 | |
> 81 | 1 | 2 | 1 | 0 | 4 | 0 | 4 | 0 | 0 | 4 | |
Total (%) | 31 (40) | 39 (50) | 8 (10) | 0 (0) | 78 (100) | 13 (18) | 48 (66) | 12 (16) | 0 (0) | 73 (100) | |
Duration of ICU stay (recovered cases), group A (n = 78), group B (n = 73) | 11-20 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 |
21-30 | 1 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | |
31-40 | 6 | 2 | 0 | 0 | 8 | 12 | 4 | 0 | 0 | 16 | |
41-50 | 5 | 4 | 0 | 0 | 9 | 8 | 0 | 0 | 0 | 8 | |
51-60 | 20 | 4 | 0 | 0 | 24 | 12 | 0 | 4 | 0 | 16 | |
61-70 | 8 | 11 | 0 | 0 | 19 | 8 | 12 | 0 | 0 | 20 | |
71-80 | 6 | 3 | 1 | 0 | 10 | 1 | 4 | 4 | 0 | 9 | |
> 81 | 1 | 2 | 1 | 0 | 4 | 0 | 4 | 0 | 0 | 4 | |
Total (%) | 49 (63) | 27 (34.5) | 2 (2.5) | 0 (0) | 78 (100) | 41 (56) | 24 (33) | 8 (11) | 0 (0) | 73 (100) | |
Duration of hospital/ICU stay (death cases), group A (n = 26), group B (n = 32) | 11-20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
21-30 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 4 | |
31-40 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |
41-50 | 0 | 7 | 0 | 0 | 7 | 12 | 0 | 0 | 0 | 12 | |
51-60 | 1 | 8 | 1 | 0 | 10 | 0 | 0 | 0 | 0 | 0 | |
61-70 | 0 | 4 | 2 | 0 | 6 | 0 | 1 | 1 | 2 | 4 | |
71-80 | 0 | 2 | 0 | 0 | 2 | 11 | 0 | 0 | 0 | 11 | |
> 81 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
Total (%) | 1 (4) | 22 (84.5) | 3 (11.5) | 0 (0) | 26 (100) | 27 (88) | 1 (3) | 1 (3) | 2 (6) | 31 (100) | |
Time to clinical improvement (recovered cases), group A (n = 78), group B (n = 73) | 11-20 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 |
21-30 | 1 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | |
31-40 | 6 | 2 | 0 | 0 | 8 | 3 | 10 | 3 | 0 | 16 | |
41-50 | 5 | 3 | 1 | 0 | 9 | 2 | 3 | 3 | 0 | 8 | |
51-60 | 17 | 6 | 1 | 0 | 24 | 7 | 9 | 0 | 0 | 16 | |
61-70 | 10 | 8 | 1 | 0 | 19 | 6 | 11 | 3 | 0 | 20 | |
71-80 | 5 | 4 | 1 | 0 | 10 | 2 | 6 | 1 | 0 | 9 | |
> 81 | 4 | 0 | 0 | 0 | 4 | 1 | 2 | 1 | 0 | 4 | |
Total (%) | 50 (64) | 24 (31) | 4 (5) | 0 (0) | 78 (100) | 21 (29) | 41 (56) | 11 (15) | 0 (0) | 73 (100) | |
Time to negative PCR (recovered cases), group A (n = 78), group B (n = 73) | 11-20 | 0 | 2 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 |
21-30 | 0 | 0 | 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | |
31-40 | 0 | 7 | 1 | 0 | 8 | 0 | 9 | 7 | 0 | 16 | |
41-50 | 0 | 7 | 1 | 1 | 9 | 0 | 4 | 4 | 0 | 8 | |
51-60 | 0 | 12 | 11 | 1 | 24 | 0 | 8 | 5 | 3 | 16 | |
61-70 | 0 | 6 | 12 | 1 | 19 | 0 | 4 | 11 | 5 | 20 | |
71-80 | 0 | 4 | 5 | 1 | 10 | 0 | 1 | 4 | 4 | 9 | |
> 81 | 0 | 3 | 0 | 1 | 4 | 0 | 0 | 4 | 0 | 4 | |
Total (%) | 0 (0) | 41 (53) | 32 (41) | 5 (6) | 78 (100) | 0 (0) | 26 (36) | 35 (48) | 12 (16) | 73 (100) | |
Time to symptomatic improvement (recovered cases), group A (n = 78), group B (n = 73) | 11-20 | 0 | 2 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 |
21-30 | 0 | 2 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | |
31-40 | 2 | 6 | 0 | 0 | 8 | 2 | 13 | 1 | 0 | 16 | |
41-50 | 4 | 4 | 1 | 0 | 9 | 0 | 6 | 2 | 0 | 8 | |
51-60 | 11 | 12 | 1 | 0 | 24 | 1 | 11 | 3 | 1 | 16 | |
61-70 | 7 | 11 | 1 | 0 | 19 | 0 | 11 | 8 | 1 | 20 | |
71-80 | 3 | 7 | 0 | 0 | 10 | 0 | 3 | 2 | 4 | 9 | |
> 81 | 1 | 3 | 0 | 0 | 4 | 0 | 1 | 3 | 0 | 4 | |
Total (%) | 28 (36) | 47 (60) | 3 (4) | 0 (0) | 78 (100) | 3 (4) | 45 (62) | 19 (26) | 6 (82) | 73 (100) |
- Citation: Mohiuddin Chowdhury ATM, Kamal A, Abbas MKU, Karim MR, Ali MA, Talukder S, Hamidullah Mehedi HM, Hassan H, Shahin AH, Li Y, He S. Role of H2 receptor blocker famotidine over the clinical recovery of COVID-19 patients: A randomized controlled trial. World J Clin Cases 2022; 10(23): 8170-8185
- URL: https://www.wjgnet.com/2307-8960/full/v10/i23/8170.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v10.i23.8170