Sequential treatment of severe pneumonia with respiratory failure and its influence on respiratory mechanical parameters and hemodynamics

Table 3 Comparison of hemodynamic parameters before and after treatment between the two groups (mean ± SD)

Group	Before treatment	Treatment 24 h	Treatment 48 h	Treatment 72 h
CVP (mmHg)
Sequential group (n = 54)	7.75 ± 0.54	8.34 ± 0.66	8.40 ± 0.58	8.38 ± 0.57
Regular group (n = 54)	7.81 ± 0.48	8.06 ± 0.53	8.23 ± 0.55	8.21 ± 0.60
t value	-0.610	2.431	1.563	1.509
P value	0.543	0.017	0.121	0.134
HR (times/min)
Sequential group (n = 54)	90.3 ± 6.9	88.8 ± 7.4	89.4 ± 7.8	88.5 ± 8.0
Regular group (n = 54)	92.0 ± 7.3	90.5 ± 8.2	88.6 ± 8.2	89.3 ± 7.4
t value	-1.244	-1.131	0.519	-0.539
P value	0.216	0.261	0.605	0.591
CO (L/min)
Sequential group (n = 54)	3.82 ± 0.67	3.94 ± 0.62	4.04 ± 0.58	4.09 ± 0.62
Regular group (n = 54)	3.90 ± 0.52	3.87 ± 0.55	3.91 ± 0.52	4.00 ± 0.57
t value	-0.693	0.621	1.226	0.785
P value	0.490	0.536	0.223	0.434
CI
Sequential group (n = 54)	3.04 ± 0.48	3.14 ± 0.51	3.11 ± 0.48	3.15 ± 0.45
Regular group (n = 54)	3.11 ± 0.42	3.04 ± 0.48	3.04 ± 0.45	3.10 ± 0.47
t value	-0.807	1.049	0.782	0.565
P value	0.422	0.296	0.436	0.573
SVV (%)
Sequential group (n = 54)	4.51 ± 0.38	4.72 ± 0.34	4.58 ± 0.41	4.59 ± 0.38
Regular group (n = 54)	4.46 ± 0.40	4.50 ± 0.38	4.34 ± 0.35	4.42 ± 0.41
t value	0.666	3.171	3.272	2.235
P value	0.507	0.002	0.001	0.028

CVP: Central venous pressure; HR: Heart rate; CO: Cardiac displacement; CI: Cardiac index; SVV: Stroke volume variation rate.