Sequential treatment of severe pneumonia with respiratory failure and its influence on respiratory mechanical parameters and hemodynamics

Table 2 Comparison of blood-gas parameters between the two groups of patients before and after treatment (mean ± SD)

Group	Before treatment	Treatment 24 h	Treatment 48 h	Treatment 72 h
PaO2 (mmHg)
Sequential group (n = 54)	36.11 ± 2.88	74.31 ± 4.17	85.32 ± 5.40	93.84 ± 5.50
Regular group (n = 54)	35.74 ± 3.01	70.58 ± 3.96	82.74 ± 4.86	91.70 ± 4.96
t value	0.653	4.766	2.610	2.123
P value	0.515	0.000	0.010	0.036
PaCO2 (mmHg)
Sequential group (n = 54)	68.42 ± 3.03	54.29 ± 3.75	45.63 ± 3.80	37.03 ± 3.94
Regular group (n = 54)	69.03 ± 2.96	55.70 ± 4.03	46.80 ± 4.25	38.64 ± 4.41
t value	-1.058	-1.882	-1.508	-2.001
P value	0.292	0.063	0.135	0.048
pH (mmHg)
Sequential group (n = 54)	7.22 ± 0.05	7.33 ± 0.05	7.37 ± 0.05	7.39 ± 0.04
Regular group (n = 54)	7.23 ± 0.05	7.31 ± 0.04	7.36 ± 0.05	7.37 ± 0.05
t value	-1.039	2.295	1.039	2.295
P value	0.301	0.024	0.301	0.024

PaO₂: Oxygen partial pressure; PaCO₂: Carbon dioxide partial pressure.