Clinical values of Barcelona Clinic Liver Cancer subgroup and up-to-7 criteria in intermediate stage hepatocellular carcinoma with transcatheter arterial chemoembolization

Table 2 The strength of association between clinical parameters and tumor objective response following transarterial chemoembolization

	Univariable analysis		Multivariable analysis
	HR (95%CI)	P value	HR (95%CI)	P value
Age	0.99 (0.97-1.02)	0.679
Sex	1.31 (0.57-2.98)	0.523
Viral hepatitis	0.75 (0.48-1.17)	0.209
Cirrhosis, Child-Pugh stage	0.99 (0.45-2.16)	0.156
ALT	1.00 (0.99-1.01)	0.281
AFP	1.00 (1.00-1.00)	0.478
HCC numbers	0.90 (0.81-1.00)	0.069	0.91 (0.81-1.02)	0.086
HCC size	0.81 (0.73-0.90)	0.002	0.81 (0.72-0.91)	0.002
Beyond up-to-7 criteria	0.24 (0.11-0.53)	0.004	0.25 (0.11-0.57)	0.009

AFP: Alpha-fetoprotein; ALT: Alanine aminotransferase; CI: Confidence interval; HCC: Hepatocellular carcinoma; HR: Hazard ratios.