Expression of hepatocyte nuclear factor 4 alpha, wingless-related integration site, and β-catenin in clinical gastric cancer

Table 5 Correlation of hepatocyte nuclear factor 4 alpha and wingless-related integration site expression with types of gastric carcinomas according to Lauren classification

Groups	n	Grade of HNF4α expression				Grade of WNT5a expression
		+ (%)	++ (%)	+++ (%)		+ (%)	++ (%)	+++ (%)
Intestinal	97	11 (11.3)	15 (15.5)		71 (73.2)	7 (7.2)	23 (23.7)	67 (69.1)
Diffuse	46	2 (4.4)	5 (10.9)		39 (84.8)	2 (4.4)	14 (30.4)	30 (65.2)
Mixed	15	0 (0.00)	0 (0.00)		15 (100.0)b	0 (0.00)	1 (6.7)	14 (93.3)d

^bP < 0.001 hepatocyte nuclear factor 4 alpha (χ² = 79.404) and ^dP < 0.001 wingless-related integration site (χ² = 80.539) vs intestinal and diffuse. HNF4α: Hepatocyte nuclear factor 4 alpha; WNT5A: Wingless-related integration site.