Network pharmacology-based strategy for predicting therapy targets of Sanqi and Huangjing in diabetes mellitus

Figure 5 The process of topological screening for the protein-protein interaction network. The yellow nodes represent the core targets and the blue nodes represent the noncore targets. A: The combined protein-protein interaction (PPI) network of the overlapping targets; B: PPI network with important targets extracted from (A); C: PPI network with important targets extracted from (B); D: PPI network with core targets extracted from (C).