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©The Author(s) 2022.
World J Clin Cases. Jul 16, 2022; 10(20): 7105-7115
Published online Jul 16, 2022. doi: 10.12998/wjcc.v10.i20.7105
Published online Jul 16, 2022. doi: 10.12998/wjcc.v10.i20.7105
Table 2 Gene detection of hereditary endometrial cancer
| Parameter | Outcome |
| Diagnosis | Hereditary EC |
| Gene (NM number) | MLH1 (NM_000249.3) |
| Nucleotide changes | Exon 6 del |
| Amino acid changes | - |
| Gene subregion | Exon 6 |
| Heterozygous | Heterozygous mutation |
| Functional changes | Deletion |
| Genetic model | AD |
| Gene mutation type | Known pathogenic mutation |
- Citation: Zhang XW, Jia ZH, Zhao LP, Wu YS, Cui MH, Jia Y, Xu TM. MutL homolog 1 germline mutation c.(453+1_454-1)_(545+1_546-1)del identified in lynch syndrome: A case report and review of literature. World J Clin Cases 2022; 10(20): 7105-7115
- URL: https://www.wjgnet.com/2307-8960/full/v10/i20/7105.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v10.i20.7105