Anesthesia and perioperative management for giant adrenal Ewing’s sarcoma with inferior vena cava and right atrium tumor thrombus: A case report

Figure 3 Pathological findings of the resected primary tumor. A: Image of the resected tumor and thrombus; B: Hematoxylin-Eosin staining shows that the tumor (the lower part of the image) was surrounded by normal adrenal tissue (the upper part of the image), which suggested that the tumor arose in the adrenal gland (2 × magnification); C: Hematoxylin-Eosin staining shows the tumor cells with round nuclei and pale cytoplasm, as well as their rosette structures (inside the yellow circles) (20 × magnification); D: Immunohistochemistry showed CD99 positive tumor cells (20 × magnification); E: Immunohistochemistry showed Nkx2.2 positive tumor cells (20 × magnification); F: Separation of the red signal and green signal (the right two signals) by fluorescence in situ hybridization reveals Ewing’s sarcoma breakpoint region 1 gene rearrangement in the nuclei of tumor cells, while the yellow signal (the left signal) shows the normal allele.