Predictive value of alarm symptoms in Rome IV irritable bowel syndrome: A multicenter cross-sectional study

doi:10.12998/wjcc.v10.i2.563

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Jan 14, 2022 (publication date) through Jan 27, 2025

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Jan 14, 2022; 10(2): 563-575
Published online Jan 14, 2022. doi: 10.12998/wjcc.v10.i2.563

Table 4 Utility of alarm symptoms for identifying organic disease

Alarm symptoms	PPV (%)
Onset age > 50 yr	10.96
Rectal bleeding	14.81
Fecal occult blood	19.35
Unintended weight loss¹	16.48
Anemia	22.92
Fever	5.56
Nocturnal symptoms	9.39
Family history of IBD, CRC or celiac disease	8.33
Anemia + fecal occult blood	69.23
Anemia + unintended weight loss	38.89
Fecal occult blood + unintended weight loss	30.00
Anemia + fecal occult blood + unintended weight loss	100.00

¹Referred to weight loss in the last 3 mo. CRC: Colorectal cancer; IBD: Inflammatory bowel disease; PPV: Positive predictive value.

Citation: Yang Q, Wei ZC, Liu N, Pan YL, Jiang XS, Tantai XX, Yang Q, Yang J, Wang JJ, Shang L, Lin Q, Xiao CL, Wang JH. Predictive value of alarm symptoms in Rome IV irritable bowel syndrome: A multicenter cross-sectional study. World J Clin Cases 2022; 10(2): 563-575
URL: https://www.wjgnet.com/2307-8960/full/v10/i2/563.htm
DOI: https://dx.doi.org/10.12998/wjcc.v10.i2.563