Intestinal mucosal barrier in functional constipation: Dose it change?

Figure 5 Immunofluorescence of colonic CD3+ intraepithelial lymphocytes and CD3+ lamina propria lymphocytes in healthy controls and patients with functional constipation. A: Colonic CD3+ intraepithelial lymphocytes (IELs) in healthy controls (Scale bar = 20 μm, white arrows represent IELs); B: Colonic CD3+ IELs in functional constipation (FC) patients (Scale bar = 20 μm, white arrows represent IELs); C: CD3+ lamina propria lymphocytes in healthy controls (Scale bar = 20 μm, orange arrows represent lymphocytes); D: CD3+ lamina propria lymphocytes in FC patients (Scale bar = 20 μm, orange arrows represent lymphocytes); E and F: CD3+ IEL and CD3+ lamina propria lymphocyte counts were not significantly different between the two groups. FC: Functional constipation; IELs: Intraepithelial lymphocytes.