Intestinal mucosal barrier in functional constipation: Dose it change?

Figure 1 Mucosal histology and goblet cells in healthy controls and patients with functional constipation. A and B: Colonic mucosal histology presented as normal in healthy controls and functional constipation (FC) patients (Scale bar = 50 μm); C: Goblet cells with Alcian Blue/Periodic acid Schiff (AB/PAS) staining in healthy controls (Scale bar = 50 μm); D: Goblet cells with AB/PAS staining in FC patients (Scale bar = 50 μm); E: The number of goblet cells per upper crypt was significantly increased in FC patients compared to healthy controls. The line inside the scatter plot indicates the mean value. FC: Functional constipation; HE: Hematoxylin and eosin.