Review of epidermal growth factor receptor-tyrosine kinase inhibitors administration to non-small-cell lung cancer patients undergoing hemodialysis

doi:10.12998/wjcc.v10.i19.6360

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Jul 6, 2022 (publication date) through Feb 8, 2025

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Jul 6, 2022; 10(19): 6360-6369
Published online Jul 6, 2022. doi: 10.12998/wjcc.v10.i19.6360

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Figure 2 Pharmacokinetics of gefitinib in patients undergoing hemodialysis and those with normal renal function. A: The C_max of gefitinib in patients undergoing HD was similar to subjects with NRF; B: One patient showed the C_trough of gefitinib was 410 ng/mL. The two patients undergoing HD showed the C_trough of gefitinib was 102-386 ng/mL; C: The plasma concentration of gefitinib were similar in patients before and after HD. C_max: Maxium concentration; C_trough: Trough concentration; HD: Hemodialysis; NRF: Normal renal function.

Citation: Lan CC, Hsieh PC, Huang CY, Yang MC, Su WL, Wu CW, Wu YK. Review of epidermal growth factor receptor-tyrosine kinase inhibitors administration to non-small-cell lung cancer patients undergoing hemodialysis. World J Clin Cases 2022; 10(19): 6360-6369
URL: https://www.wjgnet.com/2307-8960/full/v10/i19/6360.htm
DOI: https://dx.doi.org/10.12998/wjcc.v10.i19.6360