Construction and validation of a novel prediction system for detection of overall survival in lung cancer patients

Figure 1 Identification of differentially expressed genes and Weighted Gene Co-expression Network Analysis. A: The differentially expressed genes analyzed in The Cancer Genome Atlas dataset. Top 30 upregulated and downregulated genes are shown; B and C: Soft-threshold power analysis revealed the scale-free fit index and the mean connectivity of network topology; D: Hierarchical cluster analysis of the coexpression module based on the dissimilarity measurement; E: Sample clustering based on expression data used to detect the outliers; F: Dendrogram of consensus module eigen genes. Groups of eigen genes below the red line merged owing to their similarity; G: The topological overlap matrix heatmap showing the overlap between the co-expression genes.