Higher volume growth rate is associated with development of worrisome features in patients with branch duct-intraductal papillary mucinous neoplasms

doi:10.12998/wjcc.v10.i17.5667

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World Journal of Clinical Cases

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Jun 16, 2022; 10(17): 5667-5679
Published online Jun 16, 2022. doi: 10.12998/wjcc.v10.i17.5667

Table 2 Baseline and demographic characteristics of patients and cysts: subgroups

		Non-worrisome features (n = 88)	Worrisome features (n = 10)	P value
Males (%)		31 (35.2)	2 (20.0)	0.540234
Females (%)		57 (64.8)	8 (80.0)	0.540234
Median age at diagnosis (IQR)		70 (63.5-74.75)	67 (59.75-76.25)	0.58232
Familial history (%)		8 (9.1)	1 (10.0)	0.628786
History of diabetes (%)		14 (15.9)	2 (20.0)	0.904665
Diabetes onset during follow-up (%)		0 (0.0)	0 (0.0)	-
Median follow-up [mo (IQR)]		37.5 (23.25-71)	69.5 (46.5-94)	0.01828
Former smokers (%)		11 (12.5)	3 (30.0)	0.306885
Active smokers (%)		8 (9.1)	0 (0.0)	0.738111
Never smoked (%)		69 (78.4)	7 (70.0)	0.83833
Multifocal		52 (59.1)	5 (50.0)	0.830551
Largest cyst localization	Head (%)	39 (44.3)	5 (50.0)	0.994538
	Isthmus/body (%)	35 (39.8)	5 (50.0)	0.776364
	Tail (%)	14 (15.9)	0 (0.0)	0.746616
Median cyst size	a [mm (IQR)]	9 (6-13)	19 (11.25-21.25)	0.0035
	b [mm (IQR)]	10 (6-15)	18 (10.75-20.75)	0.00652
	c [mm (IQR)]	9.5 (6-15)	22.5 (12-27.65)	0.00424
EUS		14 (15.9)	5 (50.0)	0.030618
Median time to EUS (IQR)		3 (0-18.25)	29 (5.5-69.5)	0.22628
Serum CA19.9 [IU/L (IQR)], n = 25		6.2 (5.6-24.2)	23.8 (6.2-37.9)	0.1556
Serum CEA [IU/L (IQR)], n = 22		2.15 (1.28-2.93)	2.15 (1.55-2.75)	0.93624

IQR: Interquartile range; a: Sagittal (antero-posterior); b: Transversal (latero-lateral); c: Coronal (cranio-caudal).

Citation: Innocenti T, Danti G, Lynch EN, Dragoni G, Gottin M, Fedeli F, Palatresi D, Biagini MR, Milani S, Miele V, Galli A. Higher volume growth rate is associated with development of worrisome features in patients with branch duct-intraductal papillary mucinous neoplasms. World J Clin Cases 2022; 10(17): 5667-5679
URL: https://www.wjgnet.com/2307-8960/full/v10/i17/5667.htm
DOI: https://dx.doi.org/10.12998/wjcc.v10.i17.5667